Papain
Papain is enzyme of the hydrolase class that catalyzes the hydrolysis of proteins and peptides. The enzyme is obtained from the latex of the papaya, Carica papaya. It has anti-inflammatory properties and effective in relieving symptoms of episiotomy.
Primary Characteristics
It is of Natural origin and belongs to Enzyme.
Solubility in Water: soluble · Solubility in Alcohol: Insoluble · Non-proprietary name: Papain · pH: 4.8.
Pharmacokinetics
None recorded.
Advertisement
Indications
Papain is primarily indicated in conditions like Constipation, Indigestion, Pain and inflammation.
Contraindications
Papain is contraindicated in conditions like Hypersensitivity to the drug.
Dosage
Papain's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1500 mg/day | 1500 mg/day | — | PO | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Papain in overdosage may give rise to further complications which include Angioedema .
Papain is known to cause more or less tolerable side effects which are usually transient. These include Abdominal cramps, Arthiritis, Diarrhea, Hypernatremia, Hypersensitivity .
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.17.11 — Digestive enzymes