Nikethamide
Nikethamide is a respiratory stimulant. It acts directly in the respiratory centres of brain. Nikethamide is seldom useful except in respiratory depression due to severe chronic bronchitis. Not used in treatment of respiratory depression due to drug overdosage.
Primary Characteristics
It is of Synthetic origin and belongs to Nicotinic acid.
Molecular Weight: 178.23 · Solubility in Water: misible · Solubility in Alcohol: misible · Non-proprietary name: Nikethamide · pH: 6.
Pharmacokinetics
None recorded.
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Indications
Nikethamide is primarily indicated in conditions like Asphyxia, CNS depression, Respiratory depression.
Contraindications
Nikethamide is contraindicated in conditions like Porphyria, Hypersensitivity to any component of product.
Dosage
Nikethamide's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1.5 g | 1.5 g | — | IV | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Nikethamide is known to cause more or less tolerable side effects which are usually transient. These include Breathlessness , Heat sensation, Itching, Nausea, Paresthesias.
Warnings / Precautions
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.24.5 — Psychostimulants, nootropics, and neurotonics