Calcium Carbonate

Drug #121

Calcium Carbonate occuring naturally in bones, shells etc. Calcium Carbonate is used mainly as an antacid. Calcium Carbonate is used to relieve heartburn by stomach acidity. Calcium Carbonate is most commonly used as a calcium supplement.

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Primary Characteristics

It is of Synthetic origin and belongs to Calcium salt.

It is also classified under Antacids .

Molecular Weight: 100 · Solubility in Water: insoluble · Solubility in Alcohol: insoluble · Non-proprietary name: Calcium Carbonate.

Molecular structure of Calcium Carbonate

Pharmacokinetics

Distribution: Calcium Carbonate has a plasma protein binding is 50%.

Indications

Calcium Carbonate is primarily indicated in conditions like Flatulence, Heart burn, Hypocalcaemia, Peptic ulcer, Upset stomach.

Calcium Carbonate is also indicated for secondary conditions like Hyperphosphataemia, Renal failure.

Contraindications

Calcium Carbonate is contraindicated in conditions like Hypercalcaemia, Hyperthyroidism, Hypercalciuria, Nephrolithiasis, Zollinger-ellison syndrome.

Dosage

Calcium Carbonate's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
1020 mg	1020 mg	Every 24h	PO	In divided doses
Paediatric Dosage (20kg)
63.5 mg/kg	63.5 mg/kg	Every 24h	Oral	-
Neonatal Dosage (3kg)
79.37 mg/kg	79.37 mg/kg	Every 24h	oral

Drug Interactions

Unknown1 interaction

4 interactions

Moderate2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Calcium Carbonate in overdosage may give rise to further complications which include hypercalcemia with alkalosis, Hypercalciuria.

Calcium Carbonate produces potentially life-threatening effects which include Hypercalcemia, Renal failure. Careful monitoring is needed with proper medical management.

Calcium Carbonate is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Acid rebound, Belching, Constipation , Dizziness, Flatulence, Headache, Nausea, Vomiting .

Warnings / Precautions

Calcium carbonate should be used with caution in patients with kidney disease or any allergy, pre-existing cardiac arrhythmias, diarrhoea, malabsorption or diseases associated with elevated vitamin D concentrations such as sarcoidosis. Avoid taking more doses than recommended. Generally calcium salts should be avoided in patients with calcium renal calculi. Plasma-calcium concentrations should be monitored closely in patients with renal insufficiency and during parentral administration and if large doses of vitamin D are used.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Inf

0.48 gm

Tabs

1250 mg 50 mg

Multi-Ingredient Combinations

Drops

1 mg/ml

Gel

1200 mg

Liquid

160 mg/10ml

Sachet

0.3 g 1400 mg 156.7 mg 235 mg 327 mg 550 mg 600 mg

Syrup

160 mg/10ml

Tabs

0.3 g 100 mg 1000 mg 1250 mg 1400 mg 1500 mg 156.7 mg 327 mg 40 mg 50 mg 600 mg 800 mg 90 mg

Tabs Chewable

1250 mg

Tabs efr

300 mg 327 mg 670 mg

Storage Conditions

Calcium Carbonate should be stored Tab.

Drug Classification

1.27 — Vitamins, minerals, tonics, and other susbstances

Manufacturers

Manufacturers of Calcium Carbonate in Pakistan: