DrugInfoSys

Halcinonide

Also known as: Alcinonide

Drug #1145

Halcinonide is a corticosteroid (class of steroid hormones formed in the adrenal gland). Halcinonide is used to treat swelling or inflammation, or itching of skin in conditions such as eczema, dermatitis, rashes, insect bites, allergies etc.

Primary Characteristics

Halcinonide is also known as Alcinonide.

It belongs to Corticosteroid.

It belongs to Glucocorticoid agonist pharmacological group on the basis of mechanism of action and also classified in Corticosteroid Topical pharmacological group. It is also classified under Dermatological Products .

Molecular Weight: 455 · Solubility in Water: insoluble · Solubility in Alcohol: slightly soluble · Non-proprietary name: Halcinonide.

Molecular structure of Halcinonide

Pharmacokinetics

Distribution: Halcinonide has a volume of distribution is 570 l/kg.

Elimination: it is metabolised via Hepatic, plasma half-life is 23hr.

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Indications

Halcinonide is primarily indicated in conditions like Dermatitis, Inflammation.

Contraindications

Halcinonide is contraindicated in conditions like Varicella zoster infections.

Dosage

Halcinonide's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0.1 %0.1 %Every 8hTopical -
Paediatric Dosage (20kg)
0.1 %0.1 %Every 8hTopical -
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Halcinonide is known to cause more or less tolerable side effects which are usually transient. These include Acneform, Burning, Dryness , Folliculitis, Hypertrichosis , Hypopigmentation, Irritation, Itching, Skin Atrophy, Striae.

Warnings / Precautions

Halcinonide should be used with caution in patients with active tuberculosis infection of respiratory tract or in untreated fungal, bacterial or systemic viral infections. Corticosteroids should only be used systemically with great caution in the presence of congestive heart failure (CHF), recent myocardial infraction (MI), hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoporosis, peptic ulceration or renal impairment. Children may be at increase risk of some adverse effects, corticosteroid causes growth retardation and prolonged use is rarely justified. Passive immunization is recommended to non-immune patients who do come in contact with chickenpox or measles. Live vaccine should not be given to patients receiving high dose systemic corticosteroid therapy nor for atleast 3 months afterwards, killed vaccine or toxoids may be given, although the response may be attenuated. During prolong treatment with corticosteroids, patients should be examined regularly, sodium intake may need to be reduced and calcium and potassium supplement may be necessary. Patient should carry cards given full details of their corticosteroid therapy. Avoid use during pregnancy. Use nasal steroids with caution until healing has occurred.

Interference in Pathology

Halcinonide may interfere in the diagnosis of ACTH Stimulation test, Urinary free cortisol test, ACTH stimulation test.

Available Brands

None recorded.

Storage Conditions

Halcinonide should be stored Cream, Oint, Soln.

Drug Classification

  1. 1.13.3.1Corticosteroids plain