DrugInfoSys

Fluocortolone

Drug #1121

Fluocortolone is a topical corticosteroid (class of steroid hormones formed in the adrenal gland ). Fluocortolone is used to reduce swelling or inflammation and itching of skin in conditions such as psoriasis, eczema, dermatitis, rashes, and allergies etc.

Primary Characteristics

It belongs to Hydrocorticosterone.

It belongs to Glucocorticoid agonist pharmacological group on the basis of mechanism of action. It is also classified under Dermatological Products .

Molecular Weight: 376.5 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Fluocortolone.

Molecular structure of Fluocortolone

Pharmacokinetics

None recorded.

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Indications

Fluocortolone is primarily indicated in conditions like Anal fissure, Dermatosis, Haemorrhoids, Proctitis.

Contraindications

Fluocortolone is contraindicated in conditions like Syphilis, Hypersensitivity to the drug.

Dosage

Fluocortolone's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
0.025 %0.025 %Every 8hTopical
Paediatric Dosage (20kg)
2.5 mg2.5 mgEvery 8hTopical -
Neonatal Dosage (3kg)
2.5 mg2.5 mgEvery 8hTopical -

Drug Interactions

None recorded.

Side Effects

The signs and symptoms that are produced after acute overdosage of Fluocortolone are Respiratory arrest, Convulsions , Allergic skin reactions.

Warnings / Precautions

Fluocortolone should be used with caution in patients with active tuberculosis infection of respiratory tract or in untreated fungal, bacterial or systemic viral infections. Corticosteroids should only be used systemically with great caution in the presence of congestive heart failure (CHF), recent myocardial infraction (MI), hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoporosis, peptic ulceration or renal impairment. Children may be at increase risk of some adverse effects, corticosteroid causes growth retardation and prolonged use is rarely justified. Passive immunization is recommended to non-immune patients who do come in contact with chickenpox or measles. Live vaccine should not be given to patients receiving high dose systemic corticosteroid therapy nor for atleast 3 months afterwards, killed vaccine or toxoids may be given, although the response may be attenuated. During prolong treatment with corticosteroids, patients should be examined regularly, sodium intake may need to be reduced and calcium and potassium supplement may be necessary. Patient should carry cards given full details of their corticosteroid therapy. Avoid use during pregnancy.Use nasal steroids with caution until healing has occurred.

Available Brands

None recorded.

Storage Conditions

Fluocortolone should be stored Cream, Oint.

Drug Classification

  1. 1.13.3.1Corticosteroids plain