Floctafenine

Also known as: Floctafenina, Floctafeninum

Drug #1119

Floctafenine is an NSAID (non-steroidal anti-inflammatory drug). Floctafenine is used for the short-term relief of pain. It acts by blocking the production of chemicals that are involved in causing pain & inflammation.

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Primary Characteristics

Floctafenine is also known as Floctafenina, Floctafeninum.

It belongs to Anthranilic Acid.

It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action. It is also classified under Analgesics and Anti-inflammatory Agents .

Molecular Weight: 406.4 · pK_a: low · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Floctafenine · pH: 4.

Pharmacokinetics

Distribution: Floctafenine has a volume of distribution is <0.5 L/kg. plasma protein binding is >99% bound to plasma proteins.

Elimination: it is metabolised via Liver, plasma half-life is 8 hr, renal excretion is 40%.

Indications

Floctafenine is primarily indicated in conditions like Pain, Rheumatoid arthritis, Trauma.

Contraindications

Floctafenine is contraindicated in conditions like Cardiomyopathy.

Dosage

Floctafenine's dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
300 mg	300 mg	Every 4h	PO
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown5 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Floctafenine is known to cause more or less tolerable side effects which are usually transient. These include Allergic reactions, Burning micturition, Drowsiness, GI upset, Haematuria, Oedema, Photosensitivity.

Warnings / Precautions

It should not be used in patients with leber's hereditary optic atrophy and during pregnancy. It Should not be taken by anyone who is currently taking other NSAIDs. This medication may mask the signs of an infection such as a fever. It may make your skin more sensitive to the sun. So avoid excessive sun exposure. Should be used with caution in epilepsy, oedema

Interference in Pathology

Floctafenine may interfere in the diagnosis of Lowers resum thyroid hormone levels.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Tabs

200 mg

Storage Conditions

Floctafenine should be stored .

Drug Classification

1.2.1.3 — Non steroidal anti-inflammatory drugs (NSAIDs)

Manufacturers

Manufacturers of Floctafenine in Pakistan:

Aventis