Roxatidine

Drug #1000

Roxatidine used in the management of peptic ulcer disease.

Primary Characteristics

It belongs to Piperidine.

It belongs to H2-antagonist pharmacological group on the basis of mechanism of action.

Molecular Weight: 384.9 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Roxatidine.

Pharmacokinetics

Elimination: renal excretion is 90 %.

Indications

Roxatidine is primarily indicated in conditions like GI ulceration, Hyperacidity.

Roxatidine is also indicated for secondary conditions like Reflux oesophagitis.

Contraindications

Roxatidine is contraindicated in conditions like Anuria.

Dosage

Roxatidine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
112.5 mg	112.5 mg	Every 24h	PO
Paediatric Dosage (20kg)
0 – 0	—	—		Not recommended in this age group
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Roxatidine is known to cause more or less tolerable side effects which are usually transient. These include Constipation , Diarrhea, Dizziness, Headache, Nausea and vomiting, Restlessness, Skin rashes.

Warnings / Precautions

Roxitadine should be used with caution in patients with impaired kidney or liver function. Intravenous injection should be given slowly and intravenous infusion is recommended in patients with cardiovascular impairment.

Interference in Pathology

Roxatidine may interfere in the diagnosis of Increased hepatic enzyme concentrations..

Available Brands

Click on a strength to view available brands.

Single Ingredient

Tabs

150 mg 75 mg

Storage Conditions

Roxatidine should be stored .

Drug Classification

1.17.1.2 — Anti-peptic ulcerants

Manufacturers

Manufacturers of Roxatidine in Pakistan:

Everest