Potassium Chloride

Drug #975

Potassium Chloride is used to treat or prevent hypokaleamia or potassium depletion. Potassium Chloride is also used to treat fluid overload in liver failure. Potassium Chloride is given as a slow release preparation or in effervescent solutions of bicarbonate and trimethylglycine. May also be given by slow IV infusion. May need dose reduction in renal failure.

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Primary Characteristics

It is of origin and belongs to Potassium Salts .

Molecular Weight: 74.55 · Solubility in Water: 1 in 2.8 · Solubility in Alcohol: Insoluble · Non-proprietary name: Potassium Chloride · pH: 5.9 · Isotonic value: 1.19.

Molecular structure of Potassium Chloride

Pharmacokinetics

Distribution: Potassium Chloride has a volume of distribution is . plasma protein binding is .

Elimination: it is metabolised via , plasma half-life is , renal excretion is .

Indications

Potassium Chloride is primarily indicated in conditions like Electrolyte disorder, Hypokalaemia.

Potassium Chloride is also indicated for secondary conditions like Correction of severe hypokalaemia, Diarrhoea, Diuresis, Prevention of hypokalaemia, Vomiting.

Contraindications

Potassium Chloride is contraindicated in conditions like Acute dehydration.

Dosage

Potassium Chloride's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
53.3 mg/ kg	53.3 mg/ kg	Every 24h	IV
30 mEq	30 mEq	Every 12h	PO	According to the need and tolerance.
Paediatric Dosage (20kg)
223.87 mg/kg	223.87 mg/kg	Every 24h	IV Infusion	As Required
74.62 mg/kg	74.62 mg/kg	Every 8h	Oral	-
Neonatal Dosage (3kg)
223.87 mg/kg	223.87 mg/kg	Every 24h	IV Infusion	As Required
74.62 mg/kg	74.62 mg/kg	Every 8h	Oral	-

Drug Interactions

Unknown3 interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Potassium Chloride in overdosage may give rise to further complications which include Numbness , Itching, Anxiety , Chest pain , Rashes, Confusion , Chest tightness , Hives.

Potassium Chloride is known to cause more or less tolerable side effects which are usually transient. These include Diarrhea, Gas, Nausea and vomiting, Stomach discomfort.

Warnings / Precautions

Administer potassium products with caution to hypokalemic hypertensive patients, because it will lower the blood pressure.

Available Brands

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Single Ingredient

Inj

Soln

Syrup

Tabs

Tabs SR

Multi-Ingredient Combinations

Inf

0.04 g/L 0.15 g/L 0.3 g/L 1.863 g/L 2.6 g/L 4 mmol/L

Inf

Inj

Liquid

Oral Soln

Sachet

0.3 g/4.885g 0.3 g/5.177g 0.3 g/7.45g 0.37 g 1.5 g 46.6 mg

Soln

0.2984 g/1000ml 0.75 g/500ml 0.75 mg/500ml 1.5 g/L

Tabs

573 mg 7.5 mg

Storage Conditions

Potassium Chloride should be stored Inj, Tab, Syrup.

Drug Classification

1.26.1.2 — Oral potassium
2.26.2.1 — Electrolytes (NaCl, KCl & Bicarbonate) and combinations
3.27 — Vitamins, minerals, tonics, and other susbstances

Manufacturers

Manufacturers of Potassium Chloride in Pakistan: