Midecamycin (Acetate)
Midecamycin (Acetate) is a macrolide antibiotic with actions and uses similar to those of erythromycin but somewhat less active. It has been given by mouth to treat variety of bacterial infections like respiratory tract, ear, skin infections etc. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Midecamycin (Acetate) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.
Primary Characteristics
It is of Semi Synthetic origin.
It is classified in Antibiotic, Macrolide pharmacological group.
Molecular Weight: 814 · Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Midecamycin (Acetate).
Pharmacokinetics
Elimination: plasma half-life is 1.5 hr.
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Indications
Midecamycin (Acetate) is primarily indicated in conditions like Bronchitis, Laryngopharyngitis, Otitis media, Periodontitis, Pneumonia, Respiratory tract infections, Skin infections, Subcutaneous abscess, Tonsillitis.
Contraindications
Midecamycin (Acetate) is contraindicated in conditions like Hypersensitivity.
Dosage
Midecamycin (Acetate)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1.35 g | 1.35 g | Every 8h | PO | In 2-3 divided doses. |
| Paediatric Dosage (20kg) | ||||
| 10 mg/kg | 10 mg/kg | Every 8h | Oral | - |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Midecamycin (Acetate) is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Anorexia , Diarrhea, Dizziness, Elevation of liver enzymes, Eosinophilia, Eruptions, Nausea, StomatitisX, Urticaria, Vomiting .
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.6.2.2.4 — Macrolides