Ebastine

Drug #897

Ebastine is a non sedating anti-histaminic agent. Ebastine is useful for symptomatic relief of allergic conditions including allergic rhinitis and in pruritic skin disorders.

← Previous drug Next drug →

Primary Characteristics

It is of Synthetic origin and belongs to Piperidine.

It belongs to H1-antagonist pharmacological group on the basis of mechanism of action.

Molecular Weight: 469.7 · Solubility in Water: Practicaly insoluble · Solubility in Alcohol: sparingly soluble · Non-proprietary name: Ebastine.

Pharmacokinetics

None recorded.

Indications

Ebastine is primarily indicated in conditions like Allergic rhinitis, Pruritus.

Ebastine is also indicated for secondary conditions like Decongestant.

Contraindications

Ebastine is contraindicated in conditions like Diarrhoea, Hypersensitivity.

Dosage

Ebastine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
10 – 10 mg	—	Every 24h	PO
Paediatric Dosage (20kg)
0.2 mg/kg	0.2 mg/kg	Every 24h	Oral	Not recommended beloe 6 Yrs.
Neonatal Dosage (3kg)
0 – 0	—	—		Not recommended below 6 yrs.

Drug Interactions

None recorded.

Side Effects

Ebastine is known to cause more or less tolerable side effects which are usually transient. These include Asthenia , Constipation , Diarrhea, Excitement, Gastric intolerance, Headache.

Warnings / Precautions

Patients should observed caution while driving or performing other tasks requiring alertness, because may cause drowsiness. Ebastine should be used with caution in patients with liver impairment, dose should be reduce in patients with renal impairment. Avoid use in young children and use with caution in elderly patients. Topical preparation containing antihistamines should not be used on broken and eczematous skin.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Caps

10 mg

Syrup

5 mg/5ml

Tabs

10 mg 120 mg 20 mg

Multi-Ingredient Combinations

Syrup

5 mg 5 mg/5ml

Tabs

10 mg

Storage Conditions

Ebastine should be stored .

Drug Classification

1.3 — Anti-allergics (Antihistamines) and drugs used in anaphylaxis
2.13.3.3 — Antipruritics