Chymotrypsin
Chymotrypsin is a proteolytic enzyme. Chymotrypsin is secreted by the pancrease as the inactive pro-enzyme chymotripsinogen. Chymotrypsin is a serine endopeptidase that preferentially cleaves peptide bonds on the carboxyl side of amino acids with bulky hydrophobic residues, particularly tyrosine, tryptophan, phenylalanine and leucine. Chymotrypsin is effective in reducing soft tissue inflammtion especially associated with trauma.
Primary Characteristics
It is of Natural origin and belongs to Proteolytic Enzyme.
It is also classified under Opthalmic Products .
Solubility in Water: sparingly · Solubility in Alcohol: null · Non-proprietary name: Chymotrypsin · pH: 3.
Pharmacokinetics
None recorded.
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Indications
Chymotrypsin is primarily indicated in conditions like Edema, Inflammation, Oedema, Trauma.
Contraindications
Chymotrypsin is contraindicated in conditions like Peptic ulcer, Renal diseases, Hepatic disease, Tuberculosis, Hypersensitivity to any component of product.
Dosage
Chymotrypsin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 100000 IU | 100000 IU | Every 6h | PO | Half hour before meal |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Chymotrypsin is known to cause more or less tolerable side effects which are usually transient. These include Corneal edema, Hypersensitivity reactions, Uveitis.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.27 — Vitamins, minerals, tonics, and other susbstances