DrugInfoSys

Beractant

Drug #818

Beractant is a sufactant. Beractant is used to treat lung damage (respiratory distress syndrome) in pre-term infants. Beractant is administered directly to the lungs and can rapidly restore lung compliance. This composite material is designed to mimic surface-tension lowering properties of natural lung surfactant

Primary Characteristics

It is of Natural origin and belongs to .

It is classified in Lubricant pharmacological group. It is also classified under Respiratory Combination Products .

Solubility in Water: null · Solubility in Alcohol: null · Non-proprietary name: Beractant.

Molecular structure of Beractant

Pharmacokinetics

Distribution: Beractant has a volume of distribution is . plasma protein binding is .

Elimination: it is metabolised via , plasma half-life is , renal excretion is .

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Indications

Beractant is primarily indicated in conditions like Respiratory distress syndrome.

Contraindications

None recorded.

Dosage

None recorded.

Drug Interactions

None recorded.

Side Effects

Beractant is known to cause more or less tolerable side effects which are usually transient. These include Apnea , Endotracheal tube blockage, Hypercarbia, Hypertension , Hypocarbia, Hypotension , Oxygen desaturation, Pallor, Pulmonary air leaks, Vasoconstriction .

Warnings / Precautions

Rapidly affects oxygenation and lung compliance and should be restricted to a highly supervised use in a clinical setting with immediate availability of clinicians experienced with intubation and ventilatory management of premature infants. If transient episodes of bradycardia and decreased oxygen saturation occur, discontinue the dosing procedure and initiate measures to alleviate the condition; produces rapid improvements in lung oxygenation and compliance that may require immediate reductions in ventilator settings and FiO2.

Available Brands

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Single Ingredient

Storage Conditions

Beractant should be stored Susp.

Drug Classification

  1. 1.25.6Respiratory stimulants and pulmonary surfactants

Manufacturers

Manufacturers of Beractant in Pakistan: