Benzydamine
Benzydamine reduces fever, swelling and relieves the pain. Benzydamine is used topically for musculoskeletal pains and for sore throat.
Primary Characteristics
Benzydamine is also known as Benzydamine HCL.
It is of Synthetic origin and belongs to Dimethylpropylamine.
It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action. It is also classified under Analgesics and Anti-inflammatory Agents .
Molecular Weight: 309.41 · Solubility in Water: very soluble · Solubility in Alcohol: freely soluble · Non-proprietary name: Benzydamine.
Pharmacokinetics
Distribution: Benzydamine has a plasma protein binding is <20%.
Elimination: plasma half-life is 13 hrs.
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Indications
Benzydamine is primarily indicated in conditions like Inflammation, Oedema in dentistry, Post operative oedema, Post-traumatic oedema, Respiratory tract inflammation, Urogenital tract inflammation.
Contraindications
Benzydamine is contraindicated in conditions like Agitation.
Dosage
Benzydamine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.15 % | 0.15 % | Every 3h | Gargle | Swish for 30 Seconds |
| 50 mg | 50 mg | Every 8h | PO | Frequency may be increased upto 4 times/day if needed. |
| 5 % | 5 % | Every 8h | Topical | |
| Paediatric Dosage (20kg) | ||||
| 0 – 0 | — | — | — | Not Recommended in this Age Group |
| Neonatal Dosage (3kg) | ||||
| 0 – 0 | — | — | Not recommended in this age group | |
Drug Interactions
None recorded.
Side Effects
Benzydamine is known to cause more or less tolerable side effects which are usually transient. These include Burning, Dizziness, Epigastric discomfort, Nausea, Numbness , Redness, Skin rashes, Visual disorders.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.2.5 — Antirheumatics, topical
- 2.25.5 — Pharyngeal preparations