Bacampicillin

Also known as: Carampicillin

Drug #809

Penicillins are active against most bacteria especially gram positive pathogen (streptococci, staphylococci,pneumococci), some negative starins (gonococci, meningoccocci), some spirochetes and some fugi. The structure of it consists of a thiazolidine ring connected to a ß lactam ring, which is attached to a side chain.it has actions and uses similar to those of ampicillin to which Bacampicillin is rapidly hydrolyzed after its administration

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Primary Characteristics

Bacampicillin is also known as Carampicillin.

It is of Semi Synthetic origin.

It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.

Molecular Weight: 502 · Solubility in Water: soluble · Solubility in Alcohol: freely Soluble · Non-proprietary name: Bacampicillin.

Pharmacokinetics

Distribution: Bacampicillin has a plasma protein binding is 18%.

Elimination: it is metabolised via Hepatic, plasma half-life is 60 min, renal excretion is 75% (as ampicillin).

Indications

Bacampicillin is primarily indicated in conditions like Chronic bronchitis, Gonorrhoea, Respiratory tract infections, Urinary tract infection.

Contraindications

Bacampicillin is contraindicated in conditions like Hypersensitivity, Pregnancy.

Dosage

Bacampicillin's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
600 mg	600 mg	Every 12h	PO
Paediatric Dosage (20kg)
18.75 mg/kg	18.75 mg/kg	Every 12h	Oral	-
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown4 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Bacampicillin in overdosage may give rise to further complications which include Convulsions , Agranulocytosis , Seizures , Thrombocytopenic purpura , Coma , Bone marrow depression .

Bacampicillin is known to cause more or less tolerable side effects which are usually transient. These include Anemia, Anxiety, Depression, Diarrhea, Enterocolitis , Glossitis, Hallucination , Lethargy, Nausea, Twitching.

Warnings / Precautions

Bacampicillin should be used with caution in patients with medical history especially of kidney disease, stomach or intestinal problems, blood disorders and of drug allergies, especially allergies to other penicillin or cephalosporin antibiotics. Do not use this drug repeatedly or for prolong period, because use of this medication for prolonged or repeated periods may result in a secondary infection (e.g.oral, bladder or vaginal yeast infection). It should be used with caution during pregnancy or lactation.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Tabs

400 mg 800 mg

Storage Conditions

Bacampicillin should be stored Tab.

Drug Classification

1.6.2.1.1 — Penicillins

Manufacturers

Manufacturers of Bacampicillin in Pakistan:

Barrett Cirin Wilshire