Barium Sulphate

Drug #74

Barium Sulphate is used in roentgenography (radoigraphy) to make the intestinal tract opaque for X-ray examination. Barium Sulphate is also used for roentgen ray examination of colon and stomach.

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Primary Characteristics

It is of Synthetic origin and belongs to Barium Salt.

It belongs to Radiopaque Agents pharmacological group on the basis of mechanism of action and also classified in Diagnostic Aids pharmacological group.

Molecular Weight: 233 · Solubility in Water: 0.002448g/100ml at 20C · Solubility in Alcohol: insoluble · Non-proprietary name: Barium Sulphate.

Pharmacokinetics

None recorded.

Indications

Barium Sulphate is primarily indicated in conditions like Delineation of GI in ctexamination, Esophagus imaging, Ileostomy enema, Small bowel imaging, Stomach imaging.

Contraindications

Barium Sulphate is contraindicated in conditions like Tracheo-oesophageal fistula, Suspected intestinal perforation, Small bowel obstruction.

Dosage

Barium Sulphate's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
1.35 mg/kg	1.35 mg/kg	—	PO	As Required
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Barium Sulphate in overdosage may give rise to further complications which include Bacteremia.

Barium Sulphate is known to cause more or less tolerable side effects which are usually transient. These include Appendicitis, Constipation , Diarrhea.

Warnings / Precautions

Barium sulfate should not be given to patients with intestinal obstruction and care is needed in those with condition which may predisposed to obstruction. Adequate hydration should be ensured to avoid constipation. Avoid in patients with gastrointestinal perforation, and should be avoided, particularly when given rectally. Aspiration may lead to Pneumonitis.

Available Brands

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Single Ingredient

Liquid

60 %w/v

Powder

99 %w/w

Storage Conditions

Barium Sulphate should be stored Powder.

Drug Classification

1.14.2 — Radiocontrast media

Manufacturers

Manufacturers of Barium Sulphate in Pakistan:

S.Ejazuddin