Potassium Permanganate
Potassium Permanganate is a strong oxidizing agent exerts its antibacterial and antifungal propertieaction against organism susceptible to nascent oxygen. Potassium Permanganate is used for bladder irrigation, urethritis. Potassium Permanganate is used as an astringent in conditions like eczema dermatitis and ivy poisoning. Potassium Permanganate is also capable of oxidizing certain drugs and venoms. In the treatment of poisoning following oral ingestion of barbiturates, chloral hydrate and many alkaloids, gastric levage with a solution of potasium permanganate helps to destroy the poison and thus prevent absorption.
Primary Characteristics
It is of Synthetic origin and belongs to Oxidizing Agent.
It belongs to Dermatological-Antiseptic pharmacological group on the basis of mechanism of action. It is also classified under Dermatological Products .
Molecular Weight: 158 · Solubility in Alcohol: 1 in 16 · Non-proprietary name: Potassium Permanganate.
Pharmacokinetics
None recorded.
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Indications
Potassium Permanganate is primarily indicated in conditions like Bromhidrosis, Dermatophytic infections, Fungal infection, Hyperhidrosis.
Potassium Permanganate is also indicated for secondary conditions like Hypopigmentation, Infected genital lesion, Infected oral lesion.
Contraindications
Potassium Permanganate is contraindicated in conditions like Hypersensitivity to the drug.
Dosage
Potassium Permanganate's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.06 % | 0.06 % | — | Topical | As Required |
| Paediatric Dosage (20kg) | ||||
| 0.06 % | 0.06 % | — | Topical | As Required |
| Neonatal Dosage (3kg) | ||||
| 0.06 % | 0.06 % | — | Topical | As Required |
Drug Interactions
None recorded.
Side Effects
Potassium Permanganate in overdosage may give rise to further complications which include Corrosive burns , Ulceration .
Potassium Permanganate produces potentially life-threatening effects which include Nausea, Vomiting, Cyanosis, Methemoglobinemia, GI ulceration, Oral ulceration, Metabolic acidosis. Careful monitoring is needed with proper medical management.
The signs and symptoms that are produced after acute overdosage of Potassium Permanganate are Cardiopulmonary arrest, Methemoglobinemia, Hypermangnesemia, Pericarditis , Acidosis, Corrosive pleurisy.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.13.1 — Antifungals, topical