Pipothiazine

Also known as: Pipotiazine

Drug #579

Pipothiazine is a phenothiazine tranquillizer. Pipothiazine is used in psychotic disorder, agitation and confusion.

Primary Characteristics

Pipothiazine is also known as Pipotiazine .

It is of Natural origin and belongs to Pipothiazine.

It belongs to D2 antagonist pharmacological group on the basis of mechanism of action. It is also classified under Psychotherapeutic Drugs .

Molecular Weight: 714.1 · Solubility in Water: < 1 in 10000 · Solubility in Alcohol: 1 in 100 · Non-proprietary name: Pipothiazine.

Pharmacokinetics

Elimination: it is metabolised via extensive by Liver, plasma half-life is 15 - 16 days, renal excretion is < 1%.

Indications

Pipothiazine is primarily indicated in conditions like Post-operative nausea and vomiting, Psychosis.

Contraindications

Pipothiazine is contraindicated in conditions like Bone marrow depression, Coma, Narrow-angle glaucoma, CNS depression.

Dosage

Pipothiazine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
1.499 mg/kg	1.499 mg/kg	Every 24h	PO	-
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
0 – 0	—	—		Not recommended in this age group

Drug Interactions

Unknown1 interaction

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Pipothiazine in overdosage may give rise to further complications which include Tardive dyskinesia , Leucopenia, Agranulocytosis , Hemolytic anemia , Hemolytic anemia , Hypothermia , Leucocytosis , Cardiovascular symptoms .

Pipothiazine produces potentially life-threatening effects which include Neuroleptic Malignant Syndrome . Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Pipothiazine are Extrapyramidal effects .

Pipothiazine is known to cause more or less tolerable side effects which are usually transient. These include Constipation , Depression, Drowsiness, Dry mouth, Galactorrhea, Impotence, Insomnia, Nasal congestion , Nightmares, Pallor.

Warnings / Precautions

Pipothiazine should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal impairment, prostatic hypertrophy. Photosensitization may occur, caution patients to take appropriate measures (e.g. wear protective clothing or sunscreen) against exposure to sunlight or UV light. Discontinue use atleast 48 hr before myelography.

Available Brands

None recorded.

Storage Conditions

Pipothiazine should be stored Inj.

Drug Classification

1.24.1 — Drugs used in psychotic disorders