Aluminium Hydroxide and Oxide
Aluminum hydroxide is an antacid. It neutralizes and reduces stomach acidity and relieves heartburning and indigestion. Aluminium Hydroxide and Oxide is used to treat stomach upsets, ulcers or other digestive disorders. It may also be used to increase phosphate excretion when phosphate retention is associated with renal stones.
Primary Characteristics
It is of Synthetic origin and belongs to Aluminium salts.
It is also classified under Antacids .
Molecular Weight: 78 · Solubility in Water: insoluble · Solubility in Alcohol: insoluble · Non-proprietary name: Aluminium Hydroxide and Oxide.
Pharmacokinetics
None recorded.
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Indications
Aluminium Hydroxide and Oxide is primarily indicated in conditions like Calcinosis universalis, Chronic diarrhoea, Hyperparathyroidism, Hyperphosphataemia in renal failure, Nephrolithiasis, Peptic ulcer, Reflux oesophagitis, Stress ulcers prevention.
Contraindications
Aluminium Hydroxide and Oxide is contraindicated in conditions like Renal failure, Osteomalacia, Partial intestinal obstruction.
Dosage
Aluminium Hydroxide and Oxide's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 600 mg | 600 mg | — | PO | up to seven times /day. |
| 875 mg | 875 mg | Every 8h | PO | |
| 1650 mg | 1650 mg | Every 6h | PO | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| 96 mg/kg | 96 mg/kg | Every 6h | oral | |
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Aluminium Hydroxide and Oxide in overdosage may give rise to further complications which include Dementia , Proximal myopathy , Encephalopathy .
The signs and symptoms that are produced after acute overdosage of Aluminium Hydroxide and Oxide are Chronic constipation.
Aluminium Hydroxide and Oxide is known to cause more or less tolerable side effects which are usually transient. These include Constipation , Diarrhea.
Warnings / Precautions
Interference in Pathology
Aluminium Hydroxide and Oxide may interfere in the diagnosis of Estimation of Serum Phosphate , Urinary pH Test .
Available Brands
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Multi-Ingredient Combinations
Storage Conditions
Drug Classification
- 1.17.1.1 — Antacids & antiflatulents
Manufacturers
Manufacturers of Aluminium Hydroxide and Oxide in Pakistan: