Latamoxef (Na)
Latamoxef (Na) is a oxacephalosporin antibiotic. Latamoxef (Na) is used to treat a variety of bacterial infections including respiratory tract, ear, skin and urinary tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular intervals of time throughout the day and night as prescribed. Latamoxef (Na) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.
Primary Characteristics
It is of Synthetic origin and belongs to Beta Lactam.
It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group.
Molecular Weight: 564.5 · pKa: 3.7 · Solubility in Water: high · Solubility in Alcohol: insoluble · Non-proprietary name: Latamoxef (Na).
Pharmacokinetics
Absorption: Latamoxef (Na) has an oral bioavailability is 0.5% (±0.5%).
Distribution: Latamoxef (Na) has a volume of distribution is 8.51 litre. plasma protein binding is 40 %.
Elimination: plasma half-life is 1.6 hr, renal excretion is 75 %.
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Indications
Latamoxef (Na) is primarily indicated in conditions like Bone and joint infection, GI infections, Gynecological infections, Meningitis, Respiratory tract infections, Septicaemia, Skin infections, Soft tissue infections, UTI.
Contraindications
None recorded.
Dosage
Latamoxef (Na)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 32.14 mg/kg | 32.14 mg/kg | Every 24h | PO | - |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Latamoxef (Na) produces potentially life-threatening effects which include Bleeding , Hypothrombinemia, Platelet dysfunctioning. Careful monitoring is needed with proper medical management.
Latamoxef (Na) is known to cause more or less tolerable side effects which are usually transient. These include Diarrhea, Hematuria, Hyperuricemia , Pyuria, Raised serum creatinine, Skin rashes.
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.6.2.1.3 — Cephalosporins