TIGECYCLINE
Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This prevents the incorporation of amino acid residues into the elongating peptide chain, inhibiting protein synthesis and eventually bacterial cell growth.
Primary Characteristics
It belongs to glycylcycline.
Molecular Weight: 585.65 · Solubility in Water: 14.55 mg/L · Non-proprietary name: TIGECYCLINE.

Pharmacokinetics
Distribution: TIGECYCLINE has a volume of distribution is 500-700 L. plasma protein binding is 71% to 89%.
Elimination: plasma half-life is 36.9 hours..
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Indications
TIGECYCLINE is primarily indicated in conditions like Infections.
TIGECYCLINE is also indicated for secondary conditions like Abdominal infection, Skin infections.
Contraindications
None recorded.
Dosage
None recorded.
Drug Interactions
None recorded.
Side Effects
The signs and symptoms that are produced after acute overdosage of TIGECYCLINE are Dizziness, Headache, Cough .
Warnings / Precautions
Available Brands
None recorded.