Sevelamer HCl
Sevelamer HCl is non absorbed phosphate binder, indicated for the control of serum phosphorus( hyperphosphataemia) in patients with chronic kidney disease on dialysis. chemically, it is known as poly(allylamine-co-N,N'-diallyl-1,3-diamino-2-hydroxypropane) hydrochloride.
Primary Characteristics
It is of Synthetic origin and belongs to Polymeric Amine.
Molecular Weight: 186.08 · Solubility in Water: insoluble · Non-proprietary name: Sevelamer HCl.
Pharmacokinetics
None recorded.
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Indications
Sevelamer HCl is primarily indicated in conditions like Hyperphosphataemia in renal failure.
Contraindications
None recorded.
Dosage
Sevelamer HCl's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 1600 mg | 1600 mg | — | PO | with meal |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Sevelamer HCl is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Constipation , Diarrhea, Dyspepsia , Flatulence, G.I adverse reactions, Nausea, Vomiting .
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.29 — Drugs used in renal, bladder, and prostatic disorders