Gadograf
Gadograf is a diagnostic agent used for CE-MRI and CE-MRA. the contrast enhancing effect is mediated by gadobutrol consisting of gadolinium and dihydroxy-hydroxymethylpropyl-tetraazacyclododecane triacetic acid (butrol).
Primary Characteristics
Molecular Weight: 604.7 · Non-proprietary name: Gadograf.
Pharmacokinetics
Distribution: Gadograf has a plasma protein binding is negligible.
Elimination: it is metabolised via not metabolized, plasma half-life is 1.3-2.1 hours, renal excretion is 90% in 12 hours.
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Indications
Gadograf is primarily indicated in conditions like Kidney disease, Liver diseases.
Contraindications
None recorded.
Dosage
None recorded.
Drug Interactions
None recorded.
Side Effects
Gadograf in overdosage may give rise to further complications which include Anaphylactoid reactions .
Gadograf is known to cause more or less tolerable side effects which are usually transient. These include Allergic reaction, Chills, Coldness, Convulsions , dizziness, Headache, Nausea and vomiting, Syncope , Vasodilation .
Warnings / Precautions
Available Brands
None recorded.