STRONTIUM RANELATE
Also known as: Distrontium renelate,
Strontium ranelate is bone metabolism modulator; inhibits bone resorption while maintaining bone formation and Antiosteoporotic agent. It is used for the treatment of postmenopausal osteoporosis to reduce the risk of vertebral and hip fractures. Its cemical formula is C12H6N2O8SSr2.
Primary Characteristics
STRONTIUM RANELATE is also known as Distrontium renelate, .
It is also classified under Bone Metabolism .
Molecular Weight: 513.49 · Solubility in Water: freely soluble · Solubility in Alcohol: insoluble in organic solvents · Non-proprietary name: STRONTIUM RANELATE.
Pharmacokinetics
Absorption: STRONTIUM RANELATE has an oral bioavailability is 23% (±4%).
Distribution: STRONTIUM RANELATE has a volume of distribution is 1 L/Kg. plasma protein binding is 25%.
Elimination: it is metabolised via as not metabolised, plasma half-life is 60 hours, renal excretion is by kedney and also in GIT.
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Indications
STRONTIUM RANELATE is primarily indicated in conditions like Osteoporosis in postmenopausal women.
Contraindications
STRONTIUM RANELATE is contraindicated in conditions like Hypersensitivity to any component of product.
Dosage
STRONTIUM RANELATE's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 2 gm | 2 gm | Every 24h | oral | Take on empty stomach between meals, preferably at bedtime. Take at least two hours after food, milk, milk products or calcium supplements. mix only with plain water. Once reconstituted in water, the suspension is stable for 24 hours. However, it is recommended to drink the suspension immediately. after preparation |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
STRONTIUM RANELATE produces potentially life-threatening effects which include Seizures , Hypersensitivity , blood clots. Careful monitoring is needed with proper medical management.
STRONTIUM RANELATE is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Diarrhea, Eczema, Hair loss, Headache, Loose stools, Muscle cramps, Oral ulceration, Vomiting .
Warnings / Precautions
Interference in Pathology
STRONTIUM RANELATE may interfere in the diagnosis of May interfer with the determination of serum and urinary calcium..
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.18.14 — Drugs affecting bone metabolism