DrugInfoSys

Atomoxetine HCl

Also known as: Tomoxetine, Tomoxetina, Tomoxetinum

Drug #2198

Atomoxetine HCl is a norepinephrine reuptake inhibitor that was approved for the treatment of ADHD (attention-deficit hyperactivity disorder). It is proved by X-ray diffraction that Atomoxetine HCl is the R(-) isomer. It is a white to practically white solid.

Primary Characteristics

Atomoxetine HCl is also known as Tomoxetine, Tomoxetina, Tomoxetinum.

Molecular Weight: 291.82 · Solubility in Water: 27.8 mg/mL · Non-proprietary name: Atomoxetine HCl.

Molecular structure of Atomoxetine HCl

Pharmacokinetics

Distribution: Atomoxetine HCl has a plasma protein binding is 98%.

Elimination: plasma half-life is 5 hours, renal excretion is >80%.

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Indications

Atomoxetine HCl is primarily indicated in conditions like Attention deficit, Hyperactivity Disorder.

Contraindications

None recorded.

Dosage

None recorded.

Drug Interactions

9 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

The signs and symptoms that are produced after acute overdosage of Atomoxetine HCl are Agitation, Somnolence, Hyperactivity, Abdominal discomfort.

Atomoxetine HCl is known to cause more or less tolerable side effects which are usually transient. These include Gastrointestinal disturbances.

Warnings / Precautions

Atomoxetine is classified as a norepinephrine reuptake inhibitor, and is approved for use in children, adolescents, and adults. However, its efficacy has not been studied in children under six years old. Its advantage over stimulants for the treatment of ADHD is that it has less abuse potential than stimulants, is not scheduled as a controlled substance and has proven in clinical trials to offer 24 hour coverage of symptoms associated with ADHD in adults and children.

Available Brands

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Single Ingredient

Drug Classification

  1. 1.24.2.1Drugs used in depression
  2. 2.24.6Cerebrovascular drugs

Manufacturers

Manufacturers of Atomoxetine HCl in Pakistan: