DrugInfoSys

Methdilazine

Also known as: Metdilazine

Drug #1990

Methdilazine is an antihistamine with anticholinergic and sedative effects, used as the base or the hydrochloride salt as an antipruritic.

Primary Characteristics

Methdilazine is also known as Metdilazine.

It belongs to Phenothiazine.

It is also classified under Antihistamines .

Molecular Weight: 296.43 · Solubility in Water: 0.348mg/L · Non-proprietary name: Methdilazine.

Molecular structure of Methdilazine

Pharmacokinetics

None recorded.

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Indications

Methdilazine is primarily indicated in conditions like Hypersensitivity reactions, Pruritus.

Contraindications

Methdilazine is contraindicated in conditions like Epilepsy, Liver diseases, Jaundice, Blood disorders, Urinary tract disorder.

Dosage

Methdilazine's dosage details are as follows:

DoseSingle DoseFrequencyRouteInstructions
Adult Dosage
8 mg8 mgEvery 8hPOFrequency could be 2-4 times a day.
Paediatric Dosage (20kg)
4 mg4 mgfrequency could be 2-4 times a day.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

The signs and symptoms that are produced after acute overdosage of Methdilazine are Convulsions , Clumsiness, Hallucinations , Shortness of breadth, Muscular spasm.

Methdilazine is known to cause more or less tolerable side effects which are usually transient. These include Drowsiness, Dry mouth, Flushing, Loss of appetite, Restlessness, Trembling.

Warnings / Precautions

Tell the doctor in charge that you are taking this medicine before you have any skin tests for allergies. The results of the tests may be affected by this medicine. When taking Methdilazine on a regular basis, make sure your doctor knows if you are taking large amounts of aspirin at the same time (as for arthritis or rheumatism). Effects of too much aspirin, such as ringing in the ears, may be covered up by the antihistamine. Check with your doctor right away if you have symptoms of pale or blue lips, fingernails, or skin, difficult or troubled breathing, irregular, fast, slow or shallow breathing or shortness of breath. These could be signs of a condition called respiratory depression.

Available Brands

None recorded.

Storage Conditions

Methdilazine should be stored Tablets.

Drug Classification

  1. 1.3Anti-allergics (Antihistamines) and drugs used in anaphylaxis