Benzbromarone

Also known as: Benzbromaronum, Benzbromarona

Drug #1900

Benzbromarone is a uricosuric drug that reduces plasma concentrations of uric acid by blocking renal tubular reabsorption. Benzbromarone may also increase the intestinal elimination of uric acid. It has been used to treat hyperuricaemia including that associated with chronic gout. Benzbromarone is not used to treat acute attacks of gout and may exacerbate and prolong them if given during an attack; treatment should not start therefore until an acute attack has subsided.

← Previous drug Next drug →

Primary Characteristics

Benzbromarone is also known as Benzbromaronum, Benzbromarona.

Solubility in Water: insoluble · Solubility in Alcohol: sparingly soluble · Non-proprietary name: Benzbromarone.

Pharmacokinetics

Elimination: it is metabolised via Hepatic.

Indications

None recorded.

Contraindications

None recorded.

Dosage

Benzbromarone's dosage details are as follows:

Dose	Single Dose	Frequency	Route
Adult Dosage
175 mg	175 mg	—	PO
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Benzbromarone in overdosage may give rise to further complications which include Renal calculi , Hepatotoxicity , Renal colic .

Benzbromarone is known to cause more or less tolerable side effects which are usually transient. These include Diarrhea.

Warnings / Precautions

Benzbromarone should be avoided in patients with moderate or severe renal impairment, in those with uric acid renal calculi, and in those with urinary uric acid excretion rates of greater than 700 mg per 24 hours. Like other uricosurics, treatment with benzbromarone should not be started during an acute attack of gout. Similarly, an adequate fluid intake should be maintained to reduce the risk of uric acid renal calculi; additionally, alkalinisation of the urine may be considered.

Available Brands

None recorded.

Storage Conditions

Benzbromarone should be stored Tab, Oint, Gel, Cream, Lotion, Oral Soln.

Drug Classification

1.2.3 — Antigout preparations