Clotiazepam
Also known as: Y-6047
Clotiazepam is a short-acting thienodiazepine with general properties similar to those of diazepam
Primary Characteristics
Clotiazepam is also known as Y-6047, clotiazepamum.
It is of Synthetic origin.
Molecular Weight: 318.8 · Solubility in Water: 5.37e-3g/l · Non-proprietary name: Clotiazepam.
Pharmacokinetics
Distribution: Clotiazepam has a volume of distribution is 2.57l/kg. plasma protein binding is 99%.
Elimination: it is metabolised via Hepatic, plasma half-life is 6-18 hrs.
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Indications
Clotiazepam is primarily indicated in conditions like Anxiety.
Clotiazepam is also indicated for secondary conditions like Irritability.
Contraindications
None recorded.
Dosage
Clotiazepam's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 10 mg | 10 mg | Every 8h | oral | dose for anxiety total duration not 78-12 weeks. |
| 15 mg | 15 mg | Every 8h | oral | dose for insomnia duration for 4 weeks. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Clotiazepam in overdosage may give rise to further complications which include Depression of respiration.
The signs and symptoms that are produced after acute overdosage of Clotiazepam are Urinary retention, Respiratory arrest, Hypotension, Sleepiness, Ataxia, Tachycardia , Coma.
Clotiazepam is known to cause more or less tolerable side effects which are usually transient. These include Asthenia , Confusion, Drowsiness, Headache.
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.24.1 — Drugs used in psychotic disorders
- 2.24.3 — Drugs used in anxiety and sleep disorders