St.Johns Wort Extract

Drug #1885

St.Johns Wort has been used since the middle age as a valuable relaxing herb.It also has long lasting tonic effects on the whole nervous system. St. John's Wort contains hypericin that inhibits monoamine oxidase, a bodily chemical associated with depression.

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Primary Characteristics

It is of Natural origin.

Non-proprietary name: St.Johns Wort Extract.

Molecular structure of St.Johns Wort Extract

Pharmacokinetics

None recorded.

Indications

St.Johns Wort Extract is primarily indicated in conditions like Anxiety disorder, Depression, Gastric ulcer, Kidney disease, Menopausal symptoms, Mood disorder, Premenstrual syndrome.

Contraindications

St.Johns Wort Extract is contraindicated in conditions like Schizophrenia, Alzheimer's disease, Pregnancy, Breast feeding, Attention deficit hyperactivity disorder.

Dosage

St.Johns Wort Extract's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
300 – 500 mg	—	Every 8h	PO	Each dose should be taken with meals.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

22 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

St.Johns Wort Extract is known to cause more or less tolerable side effects which are usually transient. These include Anxiety, Dizziness, Dry mouth, Fatigue, Gastrointestinal disturbances, Headache, Itching, Pruritus , Rashes , Restlessness, Sedation , Skin reactions.

Warnings / Precautions

St. John's Wort makes the skin more light sensitive. Persons with fair skin should avoid exposure to strong sunlight and other sources of ultraviolet light, such as tanning beds. These individuals may suffer a dermatitis, severe burning, and possibly blistering of the skin. The severity of these effects will depend on the amount of the plant consumed and the length of exposure to sunlight.St. John's Wort should not be used at the same time as prescription antidepressants. Do not use St. John's Wort during pregnancy or lactation.

Interference in Pathology

St.Johns Wort Extract may interfere in the diagnosis of Elevated TSH levels.

Available Brands

None recorded.

Drug Classification

1.24.2.1 — Drugs used in depression
2.24.3 — Drugs used in anxiety and sleep disorders
3.27 — Vitamins, minerals, tonics, and other susbstances