Phentermine
Phentermine is a colorless mobile oily liquid amphetamine with a centrally acting sympathomimetic and weak cardiovascular activity.It is used as an ANOREXIANT.It also stimulate neurons to release or maintain high levels of catecholamines.
Primary Characteristics
It belongs to phenylethylamine.
It is classified in Adrenergic Agonist Agent pharmacological group. It is also classified under CNS Stimulant .
Molecular Weight: 149.23 · Solubility in Water: soluble · Solubility in Alcohol: soluble · Non-proprietary name: PHENTERMINE · pH: 5.
Pharmacokinetics
Distribution: Phentermine has a plasma protein binding is 96.3%.
Elimination: it is metabolised via hepatic, plasma half-life is 16 to 31 hours, renal excretion is 90%.
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Indications
Phentermine is primarily indicated in conditions like Appetite suppresser.
Phentermine is also indicated for secondary conditions like Obesity.
Contraindications
Phentermine is contraindicated in conditions like Epilepsy, Glucoma, Heart disease, Arteriosclerosis.
Dosage
Phentermine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 22.5 mg | 22.5 mg | Every 24h | oral | It is recommended to take dose before meal usually before breakfast. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
The signs and symptoms that are produced after acute overdosage of Phentermine are Coma, Delirium, Tachycardia , Convulsions .
Phentermine is known to cause more or less tolerable side effects which are usually transient. These include Blurred vision, Dizziness, Dry mouth, Nausea, Restlessness.
Warnings / Precautions
Available Brands
Drug Classification
- 1.17.10 — Antiobesity preparations
Manufacturers
Manufacturers of Phentermine in Pakistan: