Methamphetamine
Also known as: Metaphetamine
Methamphetamine is chemically identical to amphetamine used in the treatment of Attention Deficit Hyperactivity Disorder (ADHD),Nacrolepsy and in Obesity. It acts as CNS stimulant and appetite suppressant works by stimulating the release of nor-epinephrine from central adrenergic receptors. It also cause release of dopamine from mesocorticolimbic system. Methamphetamine is widely abused for its central stimulant actions.It is the drug usually called speed in drug abuse circle.
Primary Characteristics
Methamphetamine is also known as Metaphetamine.
It is of Synthetic origin.
Molecular Weight: 185.7 · Solubility in Water: Freely soluble · Solubility in Alcohol: Freely soluble · Non-proprietary name: Methamphetamine.
Pharmacokinetics
Elimination: it is metabolised via Hepatic, plasma half-life is 9-15 hr.
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Indications
Methamphetamine is primarily indicated in conditions like Attention deficit, Hyperactivity Disorder.
Methamphetamine is also indicated for secondary conditions like Obesity.
Contraindications
None recorded.
Dosage
Methamphetamine's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 5 mg | 5 mg | Every 8h | oral | Before meal |
| Paediatric Dosage (20kg) | ||||
| 5 mg | 5 mg | — | Oral | Frequecny could be 1 or 2 times a day |
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Methamphetamine in overdosage may give rise to further complications which include Tachycardia , Tremors , Tachycardia.
Methamphetamine produces potentially life-threatening effects which include Heart failure, Stroke. Careful monitoring is needed with proper medical management.
The signs and symptoms that are produced after acute overdosage of Methamphetamine are Cardiac arrhythmias, Coma, Confusion , Hyperpyrexia, Mydriasis, Chest pain, Hyperflexia .
Methamphetamine is known to cause more or less tolerable side effects which are usually transient. These include Constipation , Dizziness, Dry mouth, Headache.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.24.2.1 — Drugs used in depression