Pargyline
Also known as: Benzenemethanamine
Pargyline is a selective MAO-B inhibitor which functions by inhibiting the metabolism of catecholamines and tyramine within presynaptic nerve terminal.It is used to treat moderate to severe hypertension.
Primary Characteristics
Pargyline is also known as Benzenemethanamine.
It belongs to MAO Inhibitor pharmacological group on the basis of mechanism of action and also classified in Hypertension pharmacological group. It is also classified under Antiparkinson Agents .
Solubility in Water: 9.98e-02mg/mL · Non-proprietary name: Pargyline · pH: 4.
Pharmacokinetics
None recorded.
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Indications
Pargyline is primarily indicated in conditions like Hypertension, Parkinson's disease.
Contraindications
Pargyline is contraindicated in conditions like Liver damage, Kidney disease.
Dosage
Pargyline's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 17.5 mg | 17.5 mg | Every 24h | oral | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Pargyline in overdosage may give rise to further complications which include Vertigo , Muscle twitching , Blurred vision .
Pargyline is known to cause more or less tolerable side effects which are usually transient. These include Dizziness, Fever, Headache, Insomnia, Sweating , Vomiting .
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.9.1 — Drugs used in parkinsonism