Propiverine Hydrochloride
Smooth muscle relaxant with actions combining the effects of anticholinergics & calcium channel blockers, used orally to relax the bladder muscles in incontinence from spinal cord leisons or unstable bladder conditions. It may cause dry mouth, blurred vision & drowsiness.
Primary Characteristics
Non-proprietary name: Propiverine Hydrochloride.
Pharmacokinetics
None recorded.
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Indications
Propiverine Hydrochloride is primarily indicated in conditions like Neurogenic bladder, Severe nausea and vomiting, Urgency and incontinence.
Propiverine Hydrochloride is also indicated for secondary conditions like Urinary frequency,urgency and incontinence.
Contraindications
Propiverine Hydrochloride is contraindicated in conditions like Glucoma, Myasthenia gravis, Gastro-intestinal atony, Pregnancy, Urinary retention, Breast feeding, Phobic and obsessional states, For termination of pregnancy.
Dosage
Propiverine Hydrochloride's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 60 mg/day | 60 mg/day | — | PO | Should be given in divided doses and a daily dose of 60 mg should not be exceeded. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Propiverine Hydrochloride is known to cause more or less tolerable side effects which are usually transient. These include Abdominal discomfort, Angioedema, Blurred vision, CNS stimulation, Constipation , Diarrhea, Difficulty in micturation, Drowsiness, Dry mouth, Faintness , Headache, Nausea, Palpitation, Skin reactions, Tachycardia, Vomiting .
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.1.4 — Muscle relaxants and cholinesterase inhibitors