Tamsulosin Hydrochloride
It is used in the symptomatic treatment of urinary obstruction caused by benign prostatic hyperplasia. It is alpha 1 adrenocetor blocker, more selective for alpha 1A adrenoceptor sub type.
Primary Characteristics
Non-proprietary name: Tamsulosin Hydrochloride.
Pharmacokinetics
Distribution: Tamsulosin Hydrochloride has a volume of distribution is 55(50-60)l/kg. plasma protein binding is >98%.
Elimination: plasma half-life is 6.8(3.3-10.3)l/kg, renal excretion is <1%.
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Indications
Tamsulosin Hydrochloride is primarily indicated in conditions like Benign prostatic hyperplasia, Primary nocturnal enuresis.
Contraindications
Tamsulosin Hydrochloride is contraindicated in conditions like Postural hypotension, Hepatic impairment, Acute and chronic psychoses.
Dosage
Tamsulosin Hydrochloride's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.4 mg | 0.4 mg | Every 24h | PO | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Tamsulosin Hydrochloride is known to cause more or less tolerable side effects which are usually transient. These include Asthenia , Blurred vision, Depression, Drowsiness, Dry mouth, Edema, Erectile disturbance, Gastrointestinal disturbances, Headache, Hypersensitivity , Hypotension , Palpitation, Rhinitis , Syncope , Tachycardia.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.29 — Drugs used in renal, bladder, and prostatic disorders