Fenoldopam
Also known as: Fenoldopam methanesulfonate
Fenoldopam is a newer peripheral arteriolar dilator used for hypertensive emergencies and postoperative hypertension. It acts primarily as an agonist of Dopamine(D1) recptors resulting in dilation of peripheral arteries and natriuresis.
Primary Characteristics
Fenoldopam is also known as Fenoldopam methanesulfonate.
Molecular Weight: 401.9 · Non-proprietary name: Fenoldopam.
Pharmacokinetics
Elimination: plasma half-life is 10 min.
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Indications
Fenoldopam is primarily indicated in conditions like Hypertensive emergencies, Postoperative hypertension.
Contraindications
Fenoldopam is contraindicated in conditions like Glucoma.
Dosage
Fenoldopam's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 0.1 ug/kg/min | 0.1 ug/kg/min | — | Cont.IV inf | And the dose is then titrated upward every 15 or 20 minutes up to a max. dose of 1.6 ug/kg/min or until the desired blood pressure reduction is achieved |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Fenoldopam in overdosage may give rise to further complications which include Reflex tachycardia .
Fenoldopam is known to cause more or less tolerable side effects which are usually transient. These include Flushing, Headache, Increased intracranial pressure.
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.12.3.7 — Direct vasodilators