Iopamidol

Drug #1819

Iopamidol is an iodinated nonionic diagnostic agent, used for a variety of radiographic procedures including angiography, arhtrography, myelography, and urography. Iopamidol has also been used orally or by enema for visualization of the gastro-intestinal tract.

← Previous drug Next drug →

Primary Characteristics

It is of Synthetic origin and belongs to Iodinated non-ionic agent.

Molecular Weight: 777.1 · Solubility in Water: Freely Soluble · Solubility in Alcohol: Insoluble · Non-proprietary name: Iopamidol.

Pharmacokinetics

Distribution: Iopamidol has a plasma protein binding is low.

Elimination: plasma half-life is 2hrs.

Indications

Iopamidol is primarily indicated in conditions like Angiography, Arthrography, Myelography.

Iopamidol is also indicated for secondary conditions like Urography.

Contraindications

Iopamidol is contraindicated in conditions like Allergy, Renal impairment, Hypersensitivity to any component of product.

Dosage

Iopamidol's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
10 ml	10 ml	—	IT	Cervical myelography by lateral cervical injection: 10 mL of a solution containing the equivalent of 200 mg of iodine per mL.
12.5 ml	12.5 ml	—	IT	Lumbar and Thoracic myelography by lumbar injection: 10 to 15 mL of a solution containing the equivalent of 200 mg of iodine per m
12.5 ml	12.5 ml	—	IT	Cervical myelography by lumbar injection: 10 to 15 mL of a solution containing the equivalent of 200 mg of iodine per mL; or 10 mL of a solution containing the equivalent of 300 mg of iodine per mL.
12.5 ml	12.5 ml	—	IV	Urography, excretory: Intravenous, 50 to 100 mL of a solution containing the equivalent of 250 mg of iodine per mL; or 50 mL of a solution containing the equivalent of 300 mg of iodine per mL, by rapid administration.
130 ml	130 ml	—	IV	CT of the body: Intravenous, 130 mL of a solution containing the equivalent of 250 mg of iodine per mL; or 50 to 100 mL of a solution containing the equivalent of 300 mg of iodine per mL; or 81 mL of a solution containing the equivalent of 370 mg of iodine per mL, by rapid administration.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

1 interaction

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Iopamidol in overdosage may give rise to further complications which include Severe Renal impairement.

Iopamidol produces potentially life-threatening effects which include Anaphylactoid reactions , Bronchospasm , Bronchospasm, Dyspnea, Acute Renal Failure , Acute renal failure, Transient ECG abnormalities, Severe urticaria. Careful monitoring is needed with proper medical management.

Iopamidol is known to cause more or less tolerable side effects which are usually transient. These include Bradycardia , Coughing, dizziness, Flushing, Headache, Hypotension , Metallic taste, Nausea, Pallor, Pruritus , Rhinitis , Sensation of warmth, Sneezing, Sweating , Tachycardia, Visual disturbances, Vomiting , Weakness.

Warnings / Precautions

Iopamidol should be administered with great caution to patients with asthma or a history of allergy and should be avoided in patients with known hypersensitivity to contrast media or to iodine. Caution is needed in patients with hepatic or renal impairment or others who may be at increased risk of renal failure.

Interference in Pathology

Iopamidol may interfere in the diagnosis of Urinanalysis , Thyroid Function Test, Increased in serum creatinin.

Available Brands

Click on a strength to view available brands.

Single Ingredient

Inj

300 mg/ml 370 mg/ml

Storage Conditions

Iopamidol should be stored .

Drug Classification

1.14.2 — Radiocontrast media

Manufacturers

Manufacturers of Iopamidol in Pakistan:

Al-Habib Hoffman Navegal