Parecoxib
Parecoxib is an analgesic belongs to non-steroidal anti-inflammatory drugs (NSAIDs). Parecoxib is a prodrug of valdecoxib, used for the short-term treatment of acute post-operative pain.
Primary Characteristics
Molecular Weight: 370.42 · Non-proprietary name: Parecoxib.
Pharmacokinetics
None recorded.
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Indications
Parecoxib is primarily indicated in conditions like Short-term management of acute postoperative pain, Ulcerative colitis and crohn's disease.
Contraindications
Parecoxib is contraindicated in conditions like Congestive heart failure, Lepromatous lepra reactions.
Dosage
Parecoxib's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 40 mg | 40 mg | — | IV/IM | THis initial dose is followed by 20-40 mg every 6-12 hours. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Parecoxib is known to cause more or less tolerable side effects which are usually transient. These include Alveolar osteitis, Back pain, Bradycardia , Cerebrovascular disorders, Hypertension , Hypoesthesia, Hypokalemia , Hypotension , Increased BUN, Postoperative anemia, Pruritus , Respiratory insufficiency.
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.2.1.3 — Non steroidal anti-inflammatory drugs (NSAIDs)