Follitropin Alfa
Follitropin Alfa is a recombinant human folllicle stimulating hormone (FSH). Follitropin Alfa is used in the treatment of female infertility due to anovulation, in women who are not responded to treatment with clomiphene.
Primary Characteristics
It is of Semi Synthetic origin and belongs to Glycoprotein.
Molecular Weight: 35000 · Solubility in Water: Soluble · Non-proprietary name: Follitropin Alfa.
Pharmacokinetics
Distribution: Follitropin Alfa has a volume of distribution is 101. plasma protein binding is 0.61/hr.
Elimination: plasma half-life is 2 h.
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Indications
Follitropin Alfa is primarily indicated in conditions like Acute spasm and spasm in diagnostic procedures, Muscle relaxation (short to intermediate duration).
Follitropin Alfa is also indicated for secondary conditions like Hypogonadotrophic hypogonadism, Metastatic breast cancer.
Contraindications
Follitropin Alfa is contraindicated in conditions like Ovarian cysts, Abnormal uterine bleeding, Pituitary tumor, Hypersensitivity to the drug.
Dosage
Follitropin Alfa's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 112.5 IU | 112.5 IU | Every 24h | SC/IM | For 7-14 days Or according to patients response. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Follitropin Alfa is known to cause more or less tolerable side effects which are usually transient. These include Bruising, Itching, Pain , Redness, Sweating .
Warnings / Precautions
Available Brands
Drug Classification
- 1.18.6 — Ovulation stimulants
Manufacturers
Manufacturers of Follitropin Alfa in Pakistan: