Sodium Biphosphate

Phosphate should not generally be administered to patients with severe renal impairment. They should be avoided in patients who may have low-serum concentrations, as these may be decrease further, and in patients with infected phosphate renal calculi. Sodium Phosphate should generally be avoided in patients with congestive heart faliure (CHF), hypertension, and oedema. Serum electrolyte and renal function should be monitored during therapy, particularly if phosphates are administered parenterally. Oral or rectal sodium phosphate preparation should not be used in patients with gastro-intestinal obstruction, inflammatory bowel disease, and conditions where there is likely to be increased colonic absorption. They should be used with caution in elderly and debilitated patients, and in those with pre-existing electrolyte disturbances.