Ibandronic Acid
Also known as: Ibandronate Sodium
Ibandronic acid is a bisphosphonate, a potent inhibitor of bone resorption. Ibandronic acid is used orally or parenterally in hypercalcaemia of malignancy, and also for the reduction of bone demage in bone metastases in breast cancer.
Primary Characteristics
Ibandronic Acid is also known as Ibandronate Sodium .
It belongs to Aminobisphosphmate.
Molecular Weight: 319.2 · Non-proprietary name: Ibandronic Acid.
Pharmacokinetics
Distribution: Ibandronic Acid has a plasma protein binding is 87%.
Elimination: renal excretion is in urine.
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Indications
Ibandronic Acid is primarily indicated in conditions like Hypercalcaemia due to malignancy, Hypercalcaemia of malignancy.
Contraindications
Ibandronic Acid is contraindicated in conditions like Pregnancy, Breast feeding, Pain and inflammation (rheumatic disease).
Dosage
Ibandronic Acid's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 3 mg | 3 mg | — | IV | To maximum hypercaleamia of malignancy. |
| 6 mg | 6 mg | — | IV | Over 15 min for bone metases. |
| 125 mg | 125 mg | — | PO | Once in a month for post menopausal osteoporosis. You should take the tablet with plenty of water - never milk. You need to take it on an empty stomach, so take it at 30 minutes before you have a meal or drink, or an hour afterwards. First thing in the morning before breakfast is often a good time, as you should stay sitting or standing afterwards for an hour. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Ibandronic Acid is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Angioedema, Bone pain, Bronchospasm, Chills, Dyspepsia , Dysphagia, Fever, Hypersensitivity reactions, Influenza like syndrome , Muscle pain, Oesophagitis, Ulceration .
Warnings / Precautions
Available Brands
Drug Classification
- 1.18.14 — Drugs affecting bone metabolism