Telithromycin
A derivative of erythromycin, antibacterial spectrum of telithromycin is similar to that of macrolides and it is also active against penicillin- and erythromycin-resistant Streptococcus pneumoniae. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed .It is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.
Primary Characteristics
It is of Semi Synthetic origin.
It belongs to Antibacterial (Proetin synthesis inhibitor) pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Macrolide pharmacological group.
Non-proprietary name: Telithromycin.
Pharmacokinetics
None recorded.
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Indications
Telithromycin is primarily indicated in conditions like Prevention of relapse in duodenal ulcer, Sedation in intensive care, Severe or recurrent duodenal and gastric ulcertion, Sinusitis, Tonsillitis.
Contraindications
Telithromycin is contraindicated in conditions like Breast feeding.
Dosage
Telithromycin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 800 mg | 800 mg | Every 24h | PO | For 5 days for Beta-hemolytic streptococcal pharyngitis or tonsilitis. |
| 800 mg | 800 mg | Every 24h | PO | For 7-10 days in community-acquired pneumonia. |
| 800 mg | 800 mg | Every 24h | PO | For 5 days for sinusitis or exacerbation of chronic bronchitis. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Telithromycin is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Anorexia , Antibiotic-associated colitis, Arrhythmia, Blurred vision, Constipation , Diarrhea, Eosinophilia, Facial edema, Flatulence, Hypotension , Insomnia, Muscle cramps, Nausea and vomiting, Palpitation, Paresthesia/hyperesthesia, Pruritus .
Warnings / Precautions
Interference in Pathology
Telithromycin may interfere in the diagnosis of Abnormal LFTs , Elevation in ALT or AST, Increased transaminases levels.
Available Brands
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Single Ingredient
Drug Classification
- 1.6.2.2.4 — Macrolides