Poractant Alfa
Poractant Alfa is a pulmonary surfactant, used in the treatment of respiratory distress syndrome or hyaline membrane disease in neonates. Poractant Alfa is used for the prophylaxis of respiratory distress syndrome in preterm neonates.
Primary Characteristics
Non-proprietary name: Poractant Alfa.
Pharmacokinetics
None recorded.
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Indications
Poractant Alfa is primarily indicated in conditions like Respiratory distress syndrome.
Contraindications
Poractant Alfa is contraindicated in conditions like Acidosis, Anaemia, Hypothermia, Hypoglycaemia.
Dosage
Poractant Alfa's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 2.5 mL/kg of birth weight | 2.5 mL/kg of birth weight | — | Intra tracheal | Up to 2 subsequent doses of 1.25 mL/kg birth weight can be administered at 12-hour intervals if needed in infants who continue to require mechanical ventilation and supplemental oxygen. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
None recorded.
Side Effects
Poractant Alfa is known to cause more or less tolerable side effects which are usually transient. These include Obstruction of the endotracheal tube by mucous secretions, Pulmonary hemorrhage.
Warnings / Precautions
Available Brands
None recorded.
Drug Classification
- 1.25.6 — Respiratory stimulants and pulmonary surfactants