Acrivastine

Also known as: Proponic acid,

Drug #1696

Acrivastine is a non-sedating antihistamine structurally related to triprolidine. Acrivastine is used for symptomatic relief of allergy such as hay fever, urticaria. Incidence of antimuscarinic and sedating effects low.

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Primary Characteristics

Acrivastine is also known as Proponic acid, .

It is of Synthetic origin and belongs to Alkylamine antihistamine.

Molecular Weight: 348.44 · Non-proprietary name: Acrivastine.

Pharmacokinetics

Elimination: it is metabolised via 1.1 hours, plasma half-life is 1.5 hrs, renal excretion is 84%.

Indications

Acrivastine is primarily indicated in conditions like Decongestant, Hay fever, Rhinitis, Urticaria.

Acrivastine is also indicated for secondary conditions like Uncomplicated gonorrhoea.

Contraindications

Acrivastine is contraindicated in conditions like Renal impairment, Porphyria.

Dosage

Acrivastine's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
34 mg/day	34 mg/day	Every 8h	PO	This dose is for Allergic rhinitis and nasal congestion.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Acrivastine in overdosage may give rise to further complications which include Increased blood pressure , Bleeding , Dizziness , Fast or uneven Heartbeat.

Acrivastine produces potentially life-threatening effects which include Breathing Difficulty, Infection of Hives, Swelling of tongue or throat. Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Acrivastine are Drowsiness, Drowsiness, Restlessness , Dry mouth, Seizures.

Acrivastine is known to cause more or less tolerable side effects which are usually transient. These include Anaphylaxis, Angioedema, Anticholinergic side effects, Drowsiness, Headache, Hypersensitivity reactions, Palpitation.

Warnings / Precautions

Antihistamines (e.g Acravastine) should be used with caution in prostatic hypertrophy, urinary retention, epilepsy, glaucoma, pyloroduodenal obstruction, hepatic disease. Caution may also be required in pregnancy and breast-feeding. Children and the elderly are more susceptible to side-effects. Donot drink alcohol while taking this medicine. Ensure patient understands about medicine, how to use it.

Available Brands

None recorded.

Storage Conditions

Acrivastine should be stored Capsules.

Drug Classification

1.3 — Anti-allergics (Antihistamines) and drugs used in anaphylaxis
2.25.4 — Nasal preparations