Tenecteplase

Drug #1673

A fibrinolytic drug, which acts by activating plasminogen to form plasmin. It is used in the treatment of myocradial infarction. It is given as a bolus injection.

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Primary Characteristics

It belongs to Plasminogen Activator pharmacological group on the basis of mechanism of action and also classified in Thrombolytic Agent pharmacological group.

Non-proprietary name: Tenecteplase.

Pharmacokinetics

None recorded.

Indications

Tenecteplase is primarily indicated in conditions like Acute myocardial infarction.

Contraindications

Tenecteplase is contraindicated in conditions like Coma, Trauma, Surgery, Bleeding diathesis, Oesophageal varices, Pain management, General dose, Resistant dermatophyte infections of skin or finger nails (not toe nails), Adjunct in the treatment of P. Vivax and P. Ovale malaria (eradication of liver stages), Adjunct to quinine in the treatment of P. Falciparum malaria, Adjunct to quinine in the treatment of falciparum malaria.

Dosage

None recorded.

Drug Interactions

11 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Tenecteplase is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Black stool, Bleeding , Bruising, Constipation , Cough , Headache, Shortening of breath.

Warnings / Precautions

Tenecteplase can cause bleeding that usually is not serious. However, serious bleeding may occur in some people. To help prevent serious bleeding, carefully follow any instructions given by your health care professional. Also, move around and be handled as little as possible, and do not get out of bed on your own, unless your health care professional tells you it is all right to do so.

Available Brands

None recorded.

Drug Classification

1.12.5 — Anti-thrombotic drugs and myocardial infarction