Certoparin
Certoparin is a low molecular weight heparin anticoaggulant. Certoparin is given by SC (subcutaneous) injection in the prevention of postoperative venous thrombo-embolism.
Primary Characteristics
Certoparin is also known as Certoparina sodica.
It is of Semi Synthetic origin and belongs to anti-coagulant (low Mol weight heparin).
It is also classified under Anticoagulants .
pKa: 2.4 · Solubility in Water: soluble · Solubility in Alcohol: partially soluble · Non-proprietary name: Certoparin.
Pharmacokinetics
Distribution: Certoparin has a volume of distribution is 40-70ml/mint. plasma protein binding is high.
Elimination: plasma half-life is 1.5 hours, renal excretion is renal (major).
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Indications
Certoparin is primarily indicated in conditions like Prevention of thromboembolism.
Contraindications
Certoparin is contraindicated in conditions like Thrombocytopenia, Bleeding.
Dosage
Certoparin's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 3000 Units | 3000 Units | — | SC | 1-2 hrs before the procedure, followed by 3000 Units daily for 7 to 10 days. |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Certoparin in overdosage may give rise to further complications which include Alopecia , Osteoporosis .
Certoparin produces potentially life-threatening effects which include Pulmonary embolism. Careful monitoring is needed with proper medical management.
Certoparin is known to cause more or less tolerable side effects which are usually transient. These include Hypersensitivity reactions, Thrombocytopenia.
Warnings / Precautions
Available Brands
None recorded.
Storage Conditions
Drug Classification
- 1.10.2 — Anticoagulants/Platelet deaggregators