Cholecalciferol
Also known as: Colecalciferol
Cholecalciferol is a naturally ocurring form of vitamin D (a fat-soluble vitamin). Cholecalciferol is produced from 7-dehydrocholesterol, a sterol present in mamalian skin, by ultraviolet irradiations. It used in the treatment and prevention of vitamin D deficiency states and some other bone disorders.
Primary Characteristics
Cholecalciferol is also known as Colecalciferol.
It is of Natural origin and belongs to Sterol.
Molecular Weight: 384.6 · Solubility in Water: insoluble · Solubility in Alcohol: freely · Non-proprietary name: Cholecalciferol.

Pharmacokinetics
Elimination: plasma half-life is 14 hrs.
Advertisement
Indications
Cholecalciferol is primarily indicated in conditions like Hypocalcaemia, Rickets, Vitamin D deficiency.
Cholecalciferol is also indicated for secondary conditions like Hypoparathyroidism, Malignant neoplasms, Osteomalacia, Psoriasis.
Contraindications
Cholecalciferol is contraindicated in conditions like Hypercalcaemia, Hypersensitivity to any component of product.
Dosage
Cholecalciferol's dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 700 units | 700 units | Every 24h | PO | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Cholecalciferol in overdosage may give rise to further complications which include Hypercalcemia , Hypercalciuria, Renal damage .
The signs and symptoms that are produced after acute overdosage of Cholecalciferol are Thirst , lassitude, Headache, Anorexia , Vertigo , Polyuria, Diarrhea, Nausea, Vomiting, Sweating .
Cholecalciferol is known to cause more or less tolerable side effects which are usually transient. These include Anorexia , Diarrhea, Lassitude , Nausea and vomiting.
Warnings / Precautions
Available Brands
Storage Conditions
Drug Classification
- 1.27 — Vitamins, minerals, tonics, and other susbstances
Manufacturers
Manufacturers of Cholecalciferol in Pakistan: