Iron Sorbitol

Also known as: Iron Sorbitex

Drug #1595

Iron Sorbitol is a complex of ferric, sorbitol and citric acid, stabilised with dextrin and sorbitol. It should be used only in the treatment of proven iron-deficiency anaemia, where oral therapy is ineffective or inappropriate. Iron Sorbitol is given parenterally. Severe anaphylactoid reactions may occur after parenteral administration.

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Primary Characteristics

Iron Sorbitol is also known as Iron Sorbitex.

It is of Synthetic origin and belongs to Iron salts.

Molecular Weight: 415.39 · Solubility in Water: Soluble · Non-proprietary name: Iron Sorbitol · pH: 7.2.

Pharmacokinetics

Absorption: Iron Sorbitol has an oral bioavailability is 33% (±33%).

Elimination: plasma half-life is 3 hr.

Indications

Iron Sorbitol is primarily indicated in conditions like Iron deficiency anaemia.

Contraindications

Iron Sorbitol is contraindicated in conditions like Haemolytic anaemia, Acute leukemia, Acute liver disease, Thalassemia.

Dosage

Iron Sorbitol's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
2 ml	2 ml	—	IM	This two mL iron sorbitol contains the recommended single daily dose (100 mg) for an adult of 70 kg body weight.
Paediatric Dosage (20kg)
0 – 0	—	—		Not recommended weighing under 3 kg
Neonatal Dosage (3kg)
No data.

Drug Interactions

Unknown2 interactions

Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Side Effects

Iron Sorbitol produces potentially life-threatening effects which include Ventricular fibrillation, Anaphylaxis , Ventricular tachycardia, AV block. Careful monitoring is needed with proper medical management.

Iron Sorbitol is known to cause more or less tolerable side effects which are usually transient. These include Arthralgia, Back pain, Bronchospasm, Fever, Flushing, Headache, Hypersensitivity reactions, Light headedness, Local pain, Metallic taste, Nausea and vomiting, Tissue staining, Urticaria.

Warnings / Precautions

Iron sorbitol should be administered only by i.m. injection in the treatment of accurately diagnosed iron deficiency anemia

Available Brands

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Multi-Ingredient Combinations

Inj

75 mg/1.5ml

Drug Classification

1.10.1 — Antianemia drugs

Manufacturers

Manufacturers of Iron Sorbitol in Pakistan:

Barrett