Metacycline (HCl)
Also known as: Methacycline Hydrochloride
Should be deleted as it has been added twice.
Primary Characteristics
Metacycline (HCl) is also known as Methacycline Hydrochloride.
It is of Synthetic origin and belongs to Tetracycline.
Molecular Weight: 478.9 · Solubility in Water: 1 in 100 · Solubility in Alcohol: 1 in 300 · Non-proprietary name: Metacycline (HCl) · pH: 2.
Pharmacokinetics
Absorption: Metacycline (HCl) has an oral bioavailability is 30% (±30%).
Distribution: Metacycline (HCl) has a plasma protein binding is 80-90%.
Elimination: plasma half-life is 14-15 hr, renal excretion is 60%.
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Indications
Metacycline (HCl) is primarily indicated in conditions like Chlamydial infections, Pharyngitis, Pneumonia, Q Fever, Rickettsiae, Sinusitis, Spotted fever, Trench fever, Typhus.
Contraindications
None recorded.
Dosage
Metacycline (HCl)'s dosage details are as follows:
| Dose | Single Dose | Frequency | Route | Instructions |
|---|---|---|---|---|
| Adult Dosage | ||||
| 600 mg | 600 mg | — | In 2 divided doses 1 or 2 hour after meals. | |
| Paediatric Dosage (20kg) | ||||
| No data. | ||||
| Neonatal Dosage (3kg) | ||||
| No data. | ||||
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Metacycline (HCl) in overdosage may give rise to further complications which include Ulceration , Teeth discoloration, Hepatotoxicity , Candidiasis , Vulvo vaginitis, Enterocolitis.
The signs and symptoms that are produced after acute overdosage of Metacycline (HCl) are Nausea, Vomiting, Diarrhea.
Metacycline (HCl) is known to cause more or less tolerable side effects which are usually transient. These include Discoloration of tongue, Dry mouth, Dysphagia, Eye pigmentation, Glossitis, Pruritus , StomatitisX.
Available Brands
None recorded.
Drug Classification
- 1.6.2.2.3 — Tetracyclines