Strontium-89 Chloride
Strontium-89, in the form of strontium chloride (89Sr), is used for the palliation of pain in patients with bone metastases.
Primary Characteristics
It is of Synthetic origin.
Molecular Weight: 168.5 · pKa: 100 % Ionized · Solubility in Water: very soluble · Solubility in Alcohol: soluble · Non-proprietary name: Strontium-89 Chloride.
Pharmacokinetics
Absorption: Strontium-89 Chloride has an oral bioavailability is 19% (±19%).
Distribution: Strontium-89 Chloride has a volume of distribution is ~ 30 - 40 litre.
Elimination: plasma half-life is 47 +/- 8 hr, renal excretion is ~ 100 % unchanged.
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Indications
Strontium-89 Chloride is primarily indicated in conditions like Relief of pain by bone metastases.
Contraindications
Strontium-89 Chloride is contraindicated in conditions like Renal failure, Bone marrow depression, Urinary incontinence.
Dosage
None recorded.
Drug Interactions
Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Side Effects
Strontium-89 Chloride in overdosage may give rise to further complications which include Bone marrow depression , Sepsis, Hemorrhages.
Strontium-89 Chloride produces potentially life-threatening effects which include Pancytopenia . Careful monitoring is needed with proper medical management.
Strontium-89 Chloride is known to cause more or less tolerable side effects which are usually transient. These include Bone pain, Mild flushing.
Warnings / Precautions
Interference in Pathology
Strontium-89 Chloride may interfere in the diagnosis of None well documented.
Available Brands
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Single Ingredient
Storage Conditions
Drug Classification
- 1.8.5 — Drugs used in Palliative care