Oxitropium (Br)

Drug #1525

Oxitropium (Br) is a quaternary ammonium compound with antimuscarinic properties and peripheral actions similar to those of atropine. Oxitropium (Br) is used as a bronchodilator in the treatment of reversible airways obstruction.

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Primary Characteristics

It is of Semi Synthetic origin.

Molecular Weight: 412.3 · Solubility in Water: > 1 in 1 · Solubility in Alcohol: good · Non-proprietary name: Oxitropium (Br).

Pharmacokinetics

Absorption: Oxitropium (Br) has an oral bioavailability is 8% (±8%), pre-systemic (first-pass) metabolism accounts for 48.5% (±48.5%).

Distribution: Oxitropium (Br) has a volume of distribution is 3.6 l/Kg. plasma protein binding is 7 %.

Elimination: plasma half-life is 2.4 hr, renal excretion is 42 % unchanged (I/V), 0.2 % unchanged (Oral).

Indications

Oxitropium (Br) is primarily indicated in conditions like Airway obstruction, Reversible airways obstruction.

Contraindications

None recorded.

Dosage

None recorded.

Drug Interactions

None recorded.

Side Effects

Oxitropium (Br) is known to cause more or less tolerable side effects which are usually transient. These include Dry mouth.

Warnings / Precautions

Available Brands

None recorded.

Storage Conditions

Oxitropium (Br) should be stored Aerosol.

Drug Classification

1.25.1.2 — Inhalants