Calcium Glubionate

Also known as: Calcium Gluconate Lactobionate Monohydrate

Drug #1512

Calcium Glubionate is used in the management of hypocalcaemia and calcium deficiency states resulting from dietry deficiency or aging (e.g Osteoprosis), in combination with other calcium salts.

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Primary Characteristics

Calcium Glubionate is also known as Calcium Gluconate Lactobionate Monohydrate.

It is of Synthetic origin and belongs to Calcium salt.

Molecular Weight: 610.5 · Non-proprietary name: Calcium Glubionate.

Molecular structure of Calcium Glubionate

Pharmacokinetics

None recorded.

Indications

Calcium Glubionate is primarily indicated in conditions like Cardiopulmonary resuscitation, Hypocalcaemia, Osteoporosis prophylaxis.

Calcium Glubionate is also indicated for secondary conditions like Severe hyperkalaemia, Severe hypermagnesaemia.

Contraindications

Calcium Glubionate is contraindicated in conditions like Hypercalcaemia, Renal calculi.

Dosage

Calcium Glubionate's dosage details are as follows:

Dose	Single Dose	Frequency	Route	Instructions
Adult Dosage
10 ml	10 ml	Every 8h	PO	For hypoparathyroidism
10 ml	10 ml	Every 24h	PO	For Pseudohypoparathyroidism. Should be taken before morning meals.
10 ml	10 ml	Every 8h	PO	For Osteomalacia
15 ml	15 ml	Every 8h	PO	For hypocalcemia.
Paediatric Dosage (20kg)
No data.
Neonatal Dosage (3kg)
No data.

Drug Interactions

None recorded.

Side Effects

Calcium Glubionate in overdosage may give rise to further complications which include Sinus bradycardia , Cardiac arrhythmias, Renal calculi .

Calcium Glubionate produces potentially life-threatening effects which include Coma, Cardiac Arrest . Careful monitoring is needed with proper medical management.

The signs and symptoms that are produced after acute overdosage of Calcium Glubionate are Hypercalcemia.

Calcium Glubionate is known to cause more or less tolerable side effects which are usually transient. These include Abdominal pain, Anorexia , Constipation , GI irritation, Mental disturbances, Nausea, Syncope , Vomiting .

Warnings / Precautions

Solution of calcium salts are irritant and care should be taken to prevent extravasation during intravenous injection. Calcium glubionate should be used with caution in patients with impaired renal function, pre-existing cardiac arrhythmias, diarrhoea, malabsorption or diseases associated with elevated vitamin D concentrations such as sarcoidosis. Generally calcium salts should be avoided in patients with calcium renal calculi. Plasma-calcium concentrations should be monitored closely in patients with renal insufficiency and during parentral administration and if large doses of vitamin D are used.

Available Brands

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Single Ingredient

Syrup

1.437 g/5ml

Multi-Ingredient Combinations

Inj

0.1375 g/ml

Storage Conditions

Calcium Glubionate should be stored Syrups.

Drug Classification

1.27 — Vitamins, minerals, tonics, and other susbstances

Manufacturers

Manufacturers of Calcium Glubionate in Pakistan:

Novartis